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THe
BuScr
Interactive
Triple-Helical
collagen Building
Script
busker
- A street
musician or
public
entertainer
(dictionary).
Thrives on
feedback from
the audience
(personal
experience).
Latest
update: July
20, 2021
The paper
describing THe
BuScr is:
J.K.
Rainey
& M.C. Goh
(2004) An
interactive
triple-helical
collagen
builder. Bioinformatics
20:
2458-2459.
Paper
download
(no
subscription
required).
If you use THe
BuScr, please
cite this
paper. See the
manual for
additional,
important
references.
Please
e-mail
me with
contact
information to
be added to
our user list
and receive
information
regarding
updates the
THe BuScr.
THe BuScr
allows you to
predict the
three-dimensional
structure of a
triple-helical
collagen
molecule with
the primary
sequence of
your choice.
You have the
ability:
1. to tweak
the manner in
which the
helical
structure is
assigned;
2. to
visualize
triple-helix
stability in
terms of
predicted
local melting
temperatures;
3. to fully
customize the
open source
Tcl/Tk script
(GNU
licensed);
4. to fully
customize the
helical
parameters and
stability
measures.
5a. to predict
all-atom
Pro/Hyp (+
Ala)
side-chains
and interface
this with SCWRL
for remaining
side-chain
prediction.
5b. or, to
include
side-chain
terminal atom
predictions.
Uses method
developed in:
Rainey and Goh
(2004), J
Chem Inf
Comput Sci,
44:
817-830. Paper
(521
kB PDF).
And supplementary
material
(1.3 MB PDF.)
News:
ver.
1.07a released
- July 2021
(changes to
documentation
and
HypScwrl3.tcl
but not to
main THeBuScr
script)
ver. 1.07
released -
June 2013
ver. 1.06
released -
Oct. 2008
ver
1.05 finally
released (Dec.
2006).
New host site
at Dalhousie
University
(Nov. 2006).
To
run THeBuScr
you will need
Tcl/Tk. We
chose this
freeware
multi-platform
scripting
language due
to its
graphical
interface
capabilities
independent of
platform, the
ease with
which it
allows file
handling and
management,
and its ready
customizability.
Follow
this
link to find
Tcl/Tk for
your platform
of choice -
right click to
open in new
window.
The
goods:
By
downloading
one of these
distributions,
you are
agreeing to
the terms of
the GNU
General Public
License. Please
click here to
read it before
proceeding
with a
download.
THe
BuScr &
its
documentation
(~1.3 MB):
Version
1.07a (July
20, 2021). tgz
format
(Unix/Mac). zip
format
(Mac/Windows).
Note
to Mac users:
works from X11
or Terminal,
but not Wish
from Finder.
And:
Stability
under MS
Windows has
not been
tested yet -
please send me
feedback on
Windows
performance!
Note: Adobe
Acrobat or
Reader (free)
required to
read the
documentation.
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