Publications
Refereed journal articles (trainees listed in bold)
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Insert Title Here Insert Title Here In press: Published: 80. Jahan, S., Doyle, C., Ghimire, A., Combita, D., Rainey, J.K., Wagner, B.D., and Ahmed, M. (2024) Elucidating the role of optical activity of polymers in protein-polymer interactions. Polymers. 16: 65. view article 79. Kumar, P., Kermanshahi-Pour, A., Brar, S.K., Xu, C.C., He, Q.S., Evans, S., and Rainey, J.K. (2023) Enzymatic digestibility of lignocellulosic wood biomass: Effect of enzyme treatment in supercritical carbon dioxide and biomass pretreatment. Heliyon. 9: e21811.view article 78. Rajan, V., Prykhozhij, S.V., Pandey, A., Cohen, A.M., Rainey, J.K., and Berman, J.N. (2023) KIT D816V is dimerization-independent and activates downstream pathways frequently perturbed in mastocytosis. British Journal of Haematology. 202: 960-970.view article 77. Kumar, P., Kermanshahi-Pour, A., Brar, S.K., He, Q.S., and Rainey, J.K. (2023) Influence of elevated pressure and pressurized fluids on microenvironment and activity of enzymes. Biotechnology Advances. 68: 108219.view article 76. Simmons, J.R., Gasmi-Seabrook, G., and Rainey, J.K. (2023) Structural features, intrinsic disorder, and modularity of a pyriform spidroin 1 core repetitive domain. Biochemistry and Cell Biology. 101: 271-283.view article 75. Song, Q., Liu, X-Q., and Rainey, J.K. (2023) 1H, 15N and 13C backbone resonance assignments of the acidic domain of the human MDM2 protein. Biomolecular NMR Assignments. 17: 9-16.view article 74. Visser, Z.B.+, Verma, S.K.+, Rainey, J.K., and Frampton, J.P. (+ contributed equally; 2022) Loading and release of quercetin from contact-drawn polyvinyl alcohol fiber scaffolds. ACS Pharmacology & Translational Science. 5: 1305-1317.view article 73. Baker, L.A., Xu, L., Badichi Akher, F., Robertson, M.K., Pugsley-DeBruyn, L., Ma, C.X., Liu, X-Q., Frampton, J.P., and Rainey, J.K. (2022) Nerve growth factor-binding engineered silk films promote neuronal attachment and neurite outgrowth. Advanced Functional Materials. 32: 2205178.view article 72. Song, Q., Liu, X-Q., and Rainey, J.K. The MDMX acidic domain competes with the p53 transactivation domain for MDM2 N-terminal domain binding. Biochimica et Biophysica Acta - Molecular Cell Research. 1869: 119319.view article 71. Verma, S.K., Yaghoobi, H., Slaine, P., Baldwin, S.K., Rainey, J.K., Kreplak, L., and Frampton, J.P. (2022) Multi-pin contact drawing enables production of anisotropic collagen fiber substrates for alignment of fibroblasts and monocytes. Colloids and Surfaces B: Biointerfaces. 215: 112525.view article 70. Song, Q., Liu, X-Q., and Rainey, J.K. (2022) 1H, 15N and 13C backbone resonance assignments of the acidic domain of the human MDMX protein. Biomolecular NMR Assignments. 16: 171-178.view article 69. Dagamajalu, S., Rex, D.A.B., Suchitha, G.P., Rai, A.B., Rainey, J.K., and Prasad, T.S.K. (2022) The network map of Elabela signaling pathway in physiological and pathological conditions. Journal of Cell Communication and Signaling. 16: 145-154.view article 68. Dagamajalu, S., Rex, D.A.B., Devi Philem, P., Rainey, J.K., and Prasad, T.S.K. (2022) A network map of apelin-mediated signaling. Journal of Cell Communication and Signaling. 16: 137-143.view article 67. Nazeer, N., Simmons, J.R., Rainey, J.K., Rodriguez-Lecompte, J.C., and Ahmed, M. (2021) Antibacterial activities of physiologically stable, self-assembled peptide nanoparticles. Journal of Materials Chemistry B. 9: 9041-9054.view article 66. Phạm, T.T.T. and Rainey, J.K. (2021) On-cell nuclear magnetic resonance spectroscopy to probe cell surface interactions. Biochemistry and Cell Biology. 99: 683-692.view article 65. Tam, N.W., Chung, D., Baldwin, S.J., Simmons, J.R., Xu, L., Rainey, J.K., Dellaire, G., and Frampton, J.P. (2020) Material properties of disulfide-crosslinked hyaluronic acid hydrogels influence prostate cancer cell growth and metabolism. Journal of Materials Chemistry B. 8: 9718-9733.view article 64. Simmons, J.R., Xu, L., and Rainey, J.K. (2019) Recombinant pyriform silk fiber mechanics are modulated by wet-spinning conditions. ACS Biomaterials Science & Engineering. 5: 4985-4993.view article view article 62. Pandey, A., LeBlanc, D.M., Parmar, H.B., Phạm, T.T.T., Sarker, M., Xu, L., Duncan, R., Liu, X-Q., and Rainey, J.K. (2019) Structure, amphipathy, and topology of the membrane-proximal helix 8 influence apelin receptor plasma membrane localization. Biochimica et Biophysica Acta - Biomembranes. 1861: 183036.view article 61. Simmons, J.R., Murza, A., Lumsden, M.D., Kenward, K., Marsault, É., and Rainey, J.K. (2019) Simultaneous ligand and receptor tracking through NMR spectroscopy enabled by distinct 19F labels. International Journal of Molecular Sciences. 20: 3658.view article (Invited peer reviewed submission for Special Issue on "Structure and Function of Membrane Proteins")60. Sarker, M., Speckert, M., and Rainey, J.K. (2019) Bicelle composition-dependent modulation of phospholipid dynamics by apelin peptides. Biochemistry and Cell Biology. 97: 325-332. view article 59. Xu, L.+, Weatherbee-Martin, N.+, Liu, X-Q. and Rainey, J.K. (+contributed equally; 2019) Recombinant silk fiber properties correlate to prefibrillar self-assembly. Small. 15: 1805294.view article Featured on theBack Cover view article 57. Morash, B.+, Sarker, M.+, and Rainey, J.K. (+contributed equally; 2018) Concentration-dependent changes to diffusion and chemical shift of internal standard molecules in aqueous and micellar solutions. Journal of Biomolecular NMR. 71: 79-89.view article 56. Kenward, C., Shin, K. and Rainey, J.K. (2018) Mixed fluorotryptophan substitutions at the same residue expand the versatility of 19F protein NMR spectroscopy. Chemistry - A European Journal. 24: 3391-3396.view article view article (Peer-reviewed invited Overview Article.) 54. Shin, K., Sarker, M., Huang, S.K. and Rainey, J.K. (2017) Apelin conformational and binding equilibria upon micelle interaction primarily depend on membrane-mimetic headgroup. Scientific Reports. 7: 15433.view article 53. Xu, L., Lefèvre, T., Orrell, K.E., Meng, Q., Auger, M., Liu, X-Q. and Rainey, J.K. (2017) Structural and mechanical roles for the C-terminal non-repetitive domain become apparent in recombinant spider aciniform silk. Biomacromolecules. 18: 3678-3686.view article 52. Das, D., Shin, K., Rainey, J.K. and Fliegel L. (2017) Transmembrane segment XI of the Na+/H+ antiporter of S. pombe is a critical part of the ion translocation pore. Scientific Reports. 7: 12793.view article 51. Shin, K., Chapman, N.A., Sarker, M., Kenward, C., Huang, S.K., Weatherbee-Martin, N., Pandey, A., Dupré, D.J. and Rainey, J.K. (2017) Bioactivity of the putative apelin proprotein expands the repertoire of apelin receptor ligands. Biochimica et Biophysica Acta - General Subjects. 1861: 1901-1912.view article 50. Langelaan, D.N., Pandey, A., Sarker, M. and Rainey, J.K. (2017) Preserved transmembrane segment topology, structure, and dynamics in disparate micellar environments. The Journal of Physical Chemistry Letters. 8: 2381-2386.view article 49. Patterson, R.E., Weatherbee-Martin, N. and Rainey, J.K. (2017) Pyrene-apelin conjugation modulates fluorophore- and peptide-micelle interactions. The Journal of Physical Chemistry B. 121: 4768-4777.view article 48. Huang, S.K.+, Shin, K.+, Sarker, M. and Rainey, J.K. (+contributed equally; 2017) Apela exhibits isoform- and headgroup-dependent modulation of micelle binding, peptide conformation and dynamics. Biochimica et Biophysica Acta - Biomembranes. 1859: 767-778. Permanentview article Free download link 47. Zhong, X.Z., Zou, Y., Sun, X., Dong, G., Cao, Q., Pandey, A., Rainey, J.K., Zhu, X. and Dong, X-P. (2017) Inhibition of TRPML1 by lysosomal adenosine involved in severe combined immunodeficiency diseases. Journal of Biological Chemistry. 292: 3445-3455.view article 46. Young, B.M., Nguyen, E., Chedraw, M.A.J., Rainey, J.K. and Dupré, D.J. (2017) Differential contribution of transmembrane domains IV, V, VI, and VII to human angiotensin II type 1 receptor homomer formation. Journal of Biological Chemistry. 292: 3341-3350.view article 45. Pandey, A., Shin, K., Patterson, R.E., Liu, X-Q. and Rainey, J.K. (2016) Current strategies for protein production and purification enabling membrane protein structural biology. Biochemistry and Cell Biology. 94: 507-527.view article 44. Tremblay, M-L., Xu, L., Sarker, M., Liu, X-Q. and Rainey, J.K. (2016) Characterizing aciniform silk repetitive domain backbone dynamics and hydrodynamic modularity. International Journal of Molecular Sciences. 17: 1305.view article (Invited peer reviewed submission for Special Issue on "Silk-Based Materials: From Production to Characterization")43. Weatherbee-Martin, N., Xu, L., Hupe, A., Kreplak, L., Fudge, D.S., Liu, X-Q. and Rainey, J.K. (2016) Identification of wet-spinning and post-spin stretching methods amenable to recombinant spider aciniform silk. Biomacromolecules. 17: 2737-2746. view article 42. Sarker, M.+, Orrell, K.E.+, Xu, L., Tremblay, M-L., Bak, J.J., Liu, X-Q. and Rainey, J.K. (+contributed equally; 2016) Tracking transitions in spider wrapping silk conformation and dynamics by 19F nuclear magnetic resonance spectroscopy. Biochemistry. 55: 3048-3059. view article .41. Eftaiha, A.F., Tremblay, M-L., Rainey, J.K. and Paige, M.F. (2015) The effect of perfluorooctadecanoic acid on a model phosphatidylcholine-peptide pulmonary lung surfactant mixture. Journal of Fluorine Chemistry. 177: 55-61. view article 40. Tremblay, M-L.+, Xu, L.+, Lef�vre, T., Sarker, M., Orrell, K.E., Leclerc, J., Meng, Q., Pezolet, M., Auger, M., Liu, X-Q. and Rainey, J.K. (+ contributed equally; 2015) Spider wrapping silk fiber architecture arising from its modular soluble protein precursor. Scientific Reports. 5: 11502. view article 39. Read, J.+, Clancy, E.K.+, Sarker, M., de Antueno, R., Langelaan, D.N., Parmar, H.B., Shin, K., Rainey, J.K. and Duncan, R. (+contributed equally; 2015) Reovirus FAST proteins drive pore formation and syncytiogenesis using a novel helix-loop-helix fusion-inducing lipid packing sensor. PLoS Pathogens. 11: e1004962.view article 38. Clattenburg, L., Wigerius, M., Qi, J., Rainey, J.K., Rourke, J.L., Muruganandan, S., Sinal, C.J. and Fawcett, J.P. (2015) NOS1AP functionally associates with YAP to regulate Hippo signaling. Molecular and Cellular Biology. 35: 2265-2277.view article 37. Sarker, M., Fraser, R.E., Lumsden, M.D., Anderson, D.J. and Rainey, J.K. (2015) Characterization of variant soft nanoparticle structure and morphology in solution by NMR spectroscopy. The Journal of Physical Chemistry C. 119: 7461-7471.view article 36. Key, T., Sarker, M., de Antueno, R., Rainey, J.K. and Duncan, R. (2015) The p10 FAST protein fusion peptide functions as a cystine noose to induce cholesterol-dependent liposome fusion without liposome tubulation. Biochmica et Biophysica Acta - Biomembranes. 1848: 408-416. view article 35.Chapman, N.A., Dupr�, D.J. and Rainey, J.K. (2014) The apelin receptor: Physiology, pathology, cell signalling, and ligand modulation of a peptide-activated class A GPCR. Biochemistry and Cell Biology. 92: 431-440. view article 34. Pandey, A., Sarker, M., Liu, X-Q. and Rainey, J.K. (2014) Small expression tags enhance bacterial expression of the first three transmembrane segments of the apelin receptor. Biochemistry and Cell Biology. 92: 269-278.view article 33. Xu, L., Tremblay, M-L., Orrell, K.E., Leclerc, J., Meng, Q., Liu, X-Q. and Rainey, J.K. (2013) Nanoparticle self-assembly by a highly stable recombinant spider wrapping silk protein subunit. FEBS Letters. 587: 3273-3280.view article 32. Shin, K., Pandey, A., Liu, X-Q., Anini, Y. and Rainey, J.K. (2013) Preferential apelin-13 production by the proprotein convertase PCSK3 is implicated in obesity. FEBS Open Biology. 3: 328-333.view article (open access)31. Kehoe, S., Tremblay, M-L., Coughlan, A., Towler, M.R., Rainey, J.K., Abraham, R.J. and Boyd, D. (2013) Preliminary Investigation of the Dissolution Behavior, Cytocompatibility, Effects of Fibrinogen Conformation and Platelet Activation for Radiopaque Embolic Particles. Journal of Functional Biomaterials. 4: 89-113. view article (open access) 30. Langelaan, D.N., Reddy, T., Banks, A.W., Dellaire, G., Dupr�, D.J. and Rainey, J.K. (2013) Structural features of the apelin receptor N-terminal tail and first transmembrane segment implicated in ligand binding and receptor trafficking. Biochimica et Biophysica Acta - Biomembranes. 1828: 1471-1483.view article (freely available) PDB entry (2LOU) BMRB entry (18225)29. Ramu, T., Prasad, M., Connors, E., Mishra, A., Thomassin, J., Leblanc, J., Rainey, J.K. and Thomas, N. (2013) A novel C-terminal region within the multicargo type III secretion chaperone CesT contributes to effector secretion. Journal of Bacteriology. 195: 740-756. Pubmed link 28. Xu, L., Rainey, J.K., Meng, Q. and Liu, X-Q. (2012) Recombinant minimalist spider wrapping silk proteins capable of native-like fiber formation. PLOS ONE. 7: e50227. view article 27. Xu, L.+, Tremblay, M-L.+, Meng, Q., Liu, X-Q. and Rainey, J.K. (+contributed equally; 2012) 1H, 13C and 15N NMR assignments of the aciniform spidroin (AcSp1) repetitive domain of Argiope trifasciata wrapping silk. Biomolecular NMR Assignments. 6: 147-151. Pubmed link.view article PDF25. Langelaan, D.N.+, Ngweniform, P.+ and Rainey, J.K. (+contributed equally; 2011) Biophysical characterization of G-protein coupled receptor-peptide ligand binding. Biochemistry and Cell Biology. 89: 98-105. view article 24. Langelaan, D.N., Wieczorek, M., Blouin, C. and Rainey, J.K. (2010) Improved helix and kink characterization in membrane proteins allows evaluation of kink sequence predictors. Journal of Chemical Information and Modeling. 50: 2213-2220.view article Download link for non-subscribers; Link to MC-HELAN web interface23. Tremblay, M-L., Banks, A.W. and Rainey, J.K. (2010) The predictive accuracy of secondary chemical shifts is more affected by protein secondary structure than solvent environment. Journal of Biomolecular NMR. 46: 257-270. view article Link to CS-CHEMeleon web interface22. Langelaan, D.N. and Rainey, J.K. (2010) Membrane catalysis of peptide-receptor binding. Biochemistry and Cell Biology. 88: 203-210. Link to article 21. Reddy, T. and Rainey, J.K. (2010) Interpretation of biomolecular NMR spin relaxation parameters. Biochemistry and Cell Biology. 88: 131-142. Link to article Link to relaxation calculation web interface. 20. Reddy, T., Li, X., Fliegel, L., Sykes, B.D. and Rainey, J.K. (2010) Correlating structure, dynamics, and function in transmembrane segment VII of the Na+/H+ exchanger isoform 1. Biochimica et Biophysica Acta - Biomembranes. 1798: 94-104. Pubmed link; view article (Invited peer reviewed submission.)19. Langelaan, D.N. and Rainey, J.K. (2009) Headgroup-dependent membrane catalysis of apelin-receptor interactions is likely. The Journal of Physical Chemistry B. 113: 10465-10471. Abstract/Download (open access availability); PDB file & chemical shifts for apelin-17 bound to SDS micelles: BMRB entry 20082; chemical shifts for apelin-17 in presence of DPC micelles: BMRB entry 16275 18. Langelaan, D.N., Bebbington, E.M., Reddy, T. and Rainey, J.K. (2009) Structural insight into G-protein coupled receptor binding by apelin. Biochemistry. 48: 537-548. Abstract/Download; Download link for non-subscribers; BMRB entries with chemical shifts & PDB files: Apelin-17 at 35�C (20029). Apelin-17 at 5�C - major conformer (20030). Apelin-17 at 5�C - minor conformer (20031) 17. Reddy, T.+, Ding, J.+, Li, X., Sykes, B.D., Rainey, J.K.and Fliegel, L. (+contributed equally; 2008) Structural and functional characterization of transmembrane segment IX of the NHE1 isoform of the Na+/H+ exchanger. Journal of Biological Chemistry. 283: 22018-22030. Abstract/Download; Covering work by Dr. Rainey prior to arrival at Dalhousie: 16. Rainey, J.K., DeVries, J.S., and Sykes, B.D. (2007) Estimation and measurement of flat or solenoidal coil inductance for radiofrequency NMR coil design. Journal of Magnetic Resonance. 187: 27-37. Abstract/Download; 15.
Slepkov, E.R.,
Rainey,
J.K., Sykes,
B.D. and
Fliegel, L.
(2007)
Structural and
functional
analysis of
the Na+/H+
exchanger. Biochemical
Journal.
401:
623-633. Abstract/download;
PDF 14. Rainey,
J.K., Fliegel,
L.
and Sykes,
B.D. (2006)
Strategies for
dealing with
conformational
sampling in
structural
calculations
of flexible or
kinked
transmembrane
peptides. Biochemistry
and
Cell Biology.
84:
918-929. Abstract/download;
PDF 13.
Ding, J.+,
Rainey,
J.K.+,
Xu, C.,
Sykes, B.D.
and Fliegel,
L. (+contributed
equally; 2006)
Structural and
functional
characterization
of
transmembrane
segment VII
of the Na+/H+
exchanger
isoform 1.
Journal of
Biological
Chemistry. 281:
29817-29829. Abstract/download;
PDF 12. Baryshnikova, O.K., Rainey, J.K., and Sykes, B.D. (2005) Nuclear magnetic resonance studies of CXC chemokine receptor 4 allosteric peptide agonists in solution. Journal of Peptide Research. 66 (s1): 12-21. Abstract/download (free) 11. Rainey, J.K. and Sykes, B.D. (2005) Optimizing oriented planar supported lipid samples for solid-state protein NMR. Biophysical Journal, 89: 2792-2805. Abstract/download;10.
Rainey,
J.K.,
DeVries, J.S.,
and Sykes,
B.D. (2005) A
rotatable
flat-coil for
static
solid-state
nuclear
magnetic
resonance
spectroscopy.
Review
of
Scientific
Instruments, 76:
086102.
Abstract/download;
9. Slepkov, E.R., Rainey, J.K., Li, X., Liu, Y., Cheng, F.J., Lindhout, D.A., Sykes, B.D. and Fliegel, L. (2005) Structural and functional characterization of transmembrane segment IV of the NHE1 isoform of the Na+/H+ exchanger. Journal of Biological Chemistry. 280: 17863-17872. Abstract/download;
8.
Rainey,
J.K.
and Goh, M.C.
(2004) An
interactive
triple-helical
collagen
builder. Bioinformatics.
20:
2458-2459.
Paper
download
(no
subscription
required)
Supplementary
Information
and Tcl/Tk
Script
7.
Rainey,
J.K.
and Goh, M.C.
(2004)
Statistically
based reduced
representation
of amino acid
side-chains. Journal
of
Chemical
Information
and Computer
Sciences.
44:
817-830. PDF 6.
Rainey,
J.K.,
Wen, C.K., and
Goh, M.C.
(2002)
Hierarchical
assembly and
the onset of
banding in
fibrous long
spacing
collagen
revealed by
atomic force
microscopy. Matrix
Biology.
21:
647-661. PDF 5.
Rainey,
J.K.
and Goh, M.C.
(2002) A
statistically
derived
parameterization
for the
collagen
triple-helix.
Protein
Science.
11:
2748-2754. PDF 4.
Rainey,
J.K.
and Goh, M.C.
(2002)
Parallel
atomic force
microscopy and
NMR
spectroscopy
to investigate
self-assembled
protein-nucleotide
aggregates.
The
Journal of
Physical
Chemistry B.
106:
5553-5560. PDF 3.
Paige,
M.F., Rainey,
J.K.,
and Goh, M.C.
(2001) A study
of fibrous
long spacing
collagen
ultrastructure
and assembly
by atomic
force
microscopy. Micron.
32:
341-53. PDF 2.
Mayo,
P., Poirier,
M., Rainey,
J., and
Tam, W. (1999)
Effect of a
remote
substituent on
regioselectivity
in
oxymercuration
of
unsymmetrically
substituted
norborenes. Tetrahedron
Letters.
40:
7727-30. PDF 1.
Paige,
M.F., Rainey,
J.K.,
and Goh, M.C.
(1998) Fibrous
long spacing
collagen
ultrastructure
elucidated by
atomic force
microscopy. Biophysical
Journal.
74:
3211-16. PDF |